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Document 2542
DOCN M94A2542
TI Migration and HIV-1 seroprevalence in a rural Ugandan population.
DT 9412
AU Nunn AJ; Kamali A; Kengeya-Kayondo JF; Mulder DW; MRC(UK) Programme on
AIDS in Uganda/Uganda Virus Research; Institute, Entebbe.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):280 (abstract no. PC0040). Unique
Identifier : AIDSLINE ICA10/94370033
AB OBJECTIVES: To study the association between change of residence and
HIV-1 serostatus in a rural Ugandan population. METHODS: As part of the
annual surveillance of a population cohort of approximately 10,000
persons in a rural sub-county of South West Uganda information has been
collected on change of residence of all adults over a three year period
and its association with HIV-1 serostatus. Sera were collected by a
medical team during home visits. Antibody testing was performed at the
Uganda Virus Research Institute using two independent EIA systems and
western blot when appropriate. RESULTS: At the fourth survey round age
and sex standardised seroprevalence rates were 8.0% overall; the rate
was 5.5% for 2,130 who had not changed house since the first survey,
8.2% for 336 who moved within the village, 12.4% for 128 who moved to a
neighbouring village and 16.3% for 542 who had joined the study area
during the previous three years (P << 0.001, 3df). We also observed an
inverse relationship between years lived at the present house at the
time of the first survey and both seroprevalence and subsequent
seroincidence rates. During 3 years the standardised rate for those
remaining in the same residence fell from 8.2% to 5.5%. There was no
evidence that change of residence was on account of HIV-1 associated
death nor that those who joined were more likely to have come from a
risk arena. CONCLUSION: Change of residence is strongly associated with
an increased risk of HIV-1 infection in this rural population and is
likely to be the result of more risky sexual behaviour among those who
move. These findings need to be recognised when designing AIDS control
programmes and intervention studies.
DE Cohort Studies Human *HIV Seroprevalence *HIV-1 Risk Factors Rural
Population *Transients and Migrants Uganda/EPIDEMIOLOGY MEETING
ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).